Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1992-03-30
1993-12-14
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436520, 436525, 436816, 436817, 436822, 436901, 436523, 436533, 436534, 435973, 435807, G01N 33546
Patent
active
052701662
ABSTRACT:
The present invention relates to immunoassay methods for detecting and measuring the amount of an analyte in a sample by means of generic anti-hapten antibodies. Also disclosed are multi-analyte immunoassay methods. Reagents, devices, and kits using the anti-hapten antibodies are also disclosed. The present invention also relates to dyed erythrocytes, preferably fixed, which are coated with antibodies. Also disclosed is the use of these dyed erythrocytes in agglutination assays to detect and measure the presence of an analyte in a sample. The analyte can be a hapten, an antigen, or an antibody. Also included are agglutination assays, compositions and kits using these dyed and coated erythrocytes.
REFERENCES:
patent: 3654090 (1972-04-01), Schurrs
patent: 4678331 (1987-07-01), Perry
patent: 4745075 (1988-05-01), Haofield et al.
Seradyn, Inc., "Microparticle Immunoassay Techniques", 2nd Edition, (1988), pp. 5-6.
Kowal Robert
Parsons Robert
Yue Vincent T.
Abbott Laboratories
Kepplinger Esther L.
Wolski Susan C.
Wong Wean Khing
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