Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-08-22
2006-08-22
Saunders, David (Department: 1644)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007500, C435S007940, C436S518000, C436S815000
Reexamination Certificate
active
07094551
ABSTRACT:
Immunoassays, assay methods, antibodies and methods of producing antibodies for the detection of fibroblast growth factor-23 (FGF-23). The immunoassay and assay method preferably comprise a non-competitive, sandwich-type assay utilizing a first bound antibody having affinity to a first site of the FGF-23 molecule, and a second, labeled antibody having an affinity for a second site present upon the FGF-23 molecule. The antibodies and methods of generating the same include administering antigenic peptide fragments of the FGF-23 molecule, monitoring the antibody titre produced thereby, extracting and selecting antibodies from the antisera having a specificity for the desired antigenic region of FGF-23, and purifying same. The antibodies may be incorporated into the immunoassay of the present invention or utilized for a variety of assay-type purposes for the detection of FGF-23.
REFERENCES:
patent: 4376110 (1983-03-01), David et al.
patent: 2005/0106755 (2005-05-01), Zahradnik et al.
patent: 0161007 (2001-08-01), None
patent: 0166595 (2001-09-01), None
patent: 0208271 (2002-01-01), None
patent: 0214504 (2002-02-01), None
Lederman et al, Molecular Immunology, vol. 28, No. 11, pp. 1171-1181, 1991.
Pharis Biotec Grants Exclusive Patent License to Nichols Institute Diagnostics for Method of Detecting Active Parathyroid Hormone, Dec. 13, 2001, Print Out from Web Site, home-investing.excite.com
ews/pr/011212
ichols-granted-lic.
Jueppner Harald
Lavigne Jeffrey
Zahradnik Richard J.
Saunders David
Stetina Brunda Garred & Brucker
LandOfFree
Immunoassays, assay methods, antibodies and method of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunoassays, assay methods, antibodies and method of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunoassays, assay methods, antibodies and method of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3712876