Immunoassay wherein labeled antibody is displaced from immobiliz

Details Immunoassay wherein labeled antibody is displaced from immobiliz Immunoassay wherein labeled antibody is displaced from immobiliz

1982-10-20

1984-02-28

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving antibody fragments

210656, 435 7, 436527, 436529, 436530, 436531, 436532, 436536, 436541, 436815, G01N 3354, G01N 3356, G01N 3358

Patent

active

044342365

ABSTRACT:
A method for the rapid determination of analyte in a sample is provided. The sample is contacted with a solid phase having immobilized thereon an analyte-analogue to which there is displaceably bound a labeled anti-analyte antibody. Because the antibody has greater affinity for the analyte than the analyte-analogue, the labeled antibody is displaced from the solid phase. The complex is separated from the solid phase, and the amount of complex is measured. The measured amount is related to the amount of analyte initially present in the sample.

REFERENCES:
patent: 4039652 (1977-08-01), Adams
patent: 4119709 (1978-10-01), Holub
patent: 4125492 (1978-11-01), Cuatrecasas
patent: 4185084 (1980-01-01), Mochida
patent: 4235869 (1980-11-01), Schwarzberg
patent: 4235960 (1980-11-01), Sasse
patent: 4256725 (1981-03-01), Rutner
patent: 4257884 (1981-03-01), Lim
patent: 4298593 (1981-11-01), Ling
patent: 4330299 (1982-05-01), Cerami
Chemical Abstracts, 89:2805c (1978).

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