Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1985-06-21
1987-09-15
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 18, 435 19, 436512, 436518, 436536, 436800, 436821, 436825, 436537, G01N 3353, G01N 33536, G01N 33543, C12Q 144
Patent
active
046939709
ABSTRACT:
A method for immunoassay of an analyte in a fluid includes contacting the analyte with an antianalyte to give a bound fraction. The bound fraction activates the first component of complement whereby a substrate present in the fluid is modulated to provide a detectable signal. The signal may be detected to establish the presence or absence of the analyte in the fluid, or it may be quantitatively measured to determine the concentration of the analyte in the fluid. The invention includes a kit of materials useful in performing the method of the invention.
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Roitt, Essential Immunology, Blackwell Scientific Publications, 1980, p. 158.
Hoke Randal A.
Mize Patrick D.
O'Connell James P.
Becton Dickinson and Company
Brown Richard E.
Nucker Christine M.
Spiegel Jack
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