Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory...
Reexamination Certificate
2011-08-09
2011-08-09
Cheu, Jacob (Department: 1641)
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
C436S526000, C422S064000, C422S065000, C422S186010
Reexamination Certificate
active
07993581
ABSTRACT:
The present invention provides an immunoassay technique which enables efficient detection of antigen-antibody reaction with high sensitivity by a magnetic method using magnetic particles and a SQUID magnetic sensor or sensors. A system based on the technique includes a disk-shaped sample holder which holds on a circle a plurality of sample containers for accommodating marked samples, resulting from marking of samples with magnetic particles by antigen-antibody reaction; rotating means for rotating the holder around its central shaft; magnetizing means for magnetizing the marked samples outside a magnetic shield; and a magnetic sensor for detecting, within the magnetic shield, magnetic fields generated from the marked samples which have been magnetized. By rotation of the holder, areas fixing and holding different ones of the sample containers are successively inserted into the magnetic shield, and the magnetization of the marked samples accommodated in first ones of the sample containers and the detection of magnetic fields generated from the marked samples accommodated in second ones of the sample containers are executed in parallel.
REFERENCES:
patent: 5149967 (1992-09-01), Otaka
patent: 5473249 (1995-12-01), Chaussy et al.
patent: 5985672 (1999-11-01), Kegelman et al.
patent: 6084399 (2000-07-01), Nagaishi et al.
patent: 6123902 (2000-09-01), Koch et al.
patent: 6483303 (2002-11-01), Simmonds et al.
patent: 59-96785 (1982-11-01), None
patent: 5-264556 (1992-03-01), None
patent: 10-513551 (1996-01-01), None
patent: 11-508031 (1996-02-01), None
patent: 2001-524675 (1998-08-01), None
patent: 2001-033455 (1999-07-01), None
patent: 2001-133458 (1999-11-01), None
patent: 2003-515743 (2000-11-01), None
patent: 2003-035758 (2001-07-01), None
patent: 2003-207511 (2002-01-01), None
patent: WO 96/23227 (1996-01-01), None
patent: WO 96/27133 (1996-02-01), None
patent: WO 97/40377 (1997-03-01), None
patent: WO 99/27369 (1998-08-01), None
patent: WO 01/40790 (2000-11-01), None
Keiji Enpuku, “Biological Immunoassay with Magnetic Marker and SQUID Magnetometer”, oyo Buturi, vol. 73, No. 1, 2004, pp. 28-31, with English abstract.
Keiji Enpuku et al., “Detection of Magnetic Nanoparticles with Superconducting Quantum Interference Device (SQUID) magnetometer and Application to Immunoassays”, Jpn. J. Appl. Phys., vol. 38 (1999), pp. 1102-1105.
K. Enpuku et al, “Application of High TcSQUID Magnetometer to Biological Immunoassays”, IEEE Transactions on Applied Superconductivity, vol. 11, No. 1, Mar. 2001, pp. 661-664.
Y. R. Chemla et al., :Ultrasensitive Magnetic Biosensor for Homogeneous Immunoassay, PNAS, Dec. 19, 2000, vol. 97, No. 26, pp. 14268-14272.
Andreas Haller, et al., Low TcSQUID Measurement System for magnetic Relaxation Immunoassays in Unshielded Environment:, IEEE Transactions on Applied Superconductivity, vol. 11, No. 1, Mar. 2001, pp. 1371-1374.
SeungKyun Lee et al., “Magnetic Gradiometer Based on a High-Transition Temperature Superconducting Quantum Interference Device for Improved Sensitivity of a Biosensor”, Applied Physics Letters, vol. 81, No. 16, Oct. 14, 2002, pp. 3094-3096.
R. Kötitz et al., “SQUID Based Remanence Measurements for Immunoassays”, IEEE Transactions on Applied Superconductivity, vol. 7, No. 2, Jun. 1997, pp. 3678-3681.
K. Enpuku et al, “High TcSQUID System and Magnetic Marker for Biological Immunoassays”, IEEE Transactions on Applied Superconductivity, vol. 13, No. 2, Jun. 2003, pp. 371-376.
Kandori Akihiko
Saitoh Kazuo
Seki Yusuke
Sugita Nami
Suzuki Daisuke
A. Marquez, Esq. Juan Carlos
Cheu Jacob
Do Pensee
Hitachi , Ltd.
Stites & Harbison PLLC
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