Immunoassay reagents and methods for detecting brequinar and ana

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...

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530363, 530367, 530395, 530807, 546170, 436546, 436800, 4241931, 514453, 514462, 514 54, C12N 996, A61K 39385, C07D21520

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active

057078440

ABSTRACT:
The present invention is directed to immunoassay reagents including specific antibodies to quinoline carboxylic acids, such as brequinar; novel quinoline carboxylic acid haptens useful as standards in immunoassays or for conjugating to large molecular weight carriers as immunogens or conjugating to detectable fluorescent moieties as tracer compounds. The present invention also relates to immunoassays for detecting quinoline carboxylic acids in clinical samples, and finally to kits containing said reagents.

REFERENCES:
patent: 3812123 (1974-05-01), Otterstedt et al.
patent: 5393891 (1995-02-01), Batt et al.
Hasegawa, T. et al., J. Toxicological Sci., 11, pp. 313-319, (1986).

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