Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-05-17
2005-05-17
Chin, Christopher L. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007230, C435S007400, C435S007600, C435S007920, C435S013000, C435S452000, C435S337000, C435S338000, C435S962000, C436S518000, C436S534000, C436S548000, C530S384000, C530S388250, C530S388260, C530S389300
Reexamination Certificate
active
06893831
ABSTRACT:
The present invention provides an immunoassay for specifically measuring with high sensitivity PIVKA-II in serum or plasma through antigen-antibody reaction by adding an animal serum containing thrombin and/or an antibody reacting with human fibrin-like related substances to the reagents. The immunoassay of the invention comprises the steps of adding thrombin and/or an antibody reacting with human fibrin-like related substances to the reagents, and measuring PIVKA-II in serum or plasma.
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Lämmle et al., 1985. “Formation of the fibrin clot: the balance of procoagulant and inhibitory factors,” inClinics In Haematology. Coagulation Disorders.(Ruggeri, ed.) W.B. Saunders Company, London. pp. 281-285.*
Weir, 1978.Handbook of Experimental Immunology.Blackwell Scientific Publications, Oxford. p. 12. 13.
Asai Tomohide
Asai Yoshiyuki
Kanashima Motohito
Takahashi Hiroki
Grun James L.
Sanko Junyaku Co. Ltd.
Wenderoth , Lind & Ponack, L.L.P.
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