Immunoassay microparticle washing system and method of use

Liquid purification or separation – Processes – Separating

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210789, 210518, 210927, 436177, 436807, 422101, B01D 2126

Patent

active

044863152

ABSTRACT:
A particle washing system and method of use provides for the placement of the fluid containing the desired particles within an inner tube having near the bottom thereof an orifice plugged with a material for sealing the particulate containing fluid from a wash fluid under forces substantially equal to 1G. The inner tube is positioned within an outer tube which contains a wash fluid having a density at least equal to that of the particle containing solution but less than that of the particles. Application of centrifugal force, substantially greater than 1G, and directed toward the bottom of the outer tube, causes the sealing material to be dislodged thereby permitting the particles to move through the orifice and through the outer solution. Thus the particles are collected from the inner solution, washed by the outer solution, and pelleted at the bottom of the outer tube.

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