Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1981-04-09
1983-11-08
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435810, 436518, 436528, 436538, 436808, G01N 3354
Patent
active
044143249
ABSTRACT:
An improved immunoassay sample determination process for determining the presence of a component of an antigen-antibody reaction in a sample is disclosed which substantially eliminates non-specific interactions between the sample and the reaction vessel wall surfaces during the antigen-antibody reaction, to thereby greatly increase the accuracy of the process. In practice, a site-deactivating medium such as an animal- or vegetable-derived total biological fluid or extract (e.g., plasma or gelatin) is covalently bound to the vessel wall surfaces for deactivation purposes. In preferred forms the process is solid-state, wherein one of the components of the antigen-antibody reaction is coupled covalently to the coating medium, and a reaction mixture fraction including the sample being determined and the other component which has been labeled, for instance by means of a colorimetrically active enzyme.
REFERENCES:
patent: 3790663 (1974-02-01), Garrison et al.
patent: 3904367 (1975-09-01), Golibersuch
patent: 3932141 (1976-01-01), Beall et al.
patent: 3960489 (1976-06-01), Giaver
patent: 3966556 (1976-06-01), Rubenstein et al.
patent: 4001583 (1977-01-01), Barrett
patent: 4016043 (1977-04-01), Schuurs et al.
patent: 4066512 (1978-01-01), Lai et al.
patent: 4066744 (1978-01-01), Price et al.
patent: 4067959 (1978-01-01), Bolz
patent: 4069352 (1978-01-01), Parsons
patent: 4070246 (1978-01-01), Kennedy et al.
patent: 4092116 (1978-05-01), Giaver
patent: 4157280 (1979-06-01), Halbert et al.
patent: 4166844 (1979-09-01), Tu
patent: 4267270 (1981-05-01), Stout
patent: 4352884 (1982-10-01), Nakashima et al.
patent: 4357142 (1982-11-01), Schall et al.
patent: 4363634 (1982-12-01), Schall
BMA Laboratory Services, Inc.
Wiseman Thomas G.
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