Immunoassay for zoxazolamine

Details Immunoassay for zoxazolamine Immunoassay for zoxazolamine

1978-04-07

1980-02-19

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 260112B, 424 12, G01N 3316, A61K 3900, A61B 1000

Patent

active

041894634

ABSTRACT:
The preparation of immunogens and selective antibodies for zoxazolamine therefrom as well as an immunoassay for zoxazolamine using said antibodies is described. Such immunoassay can be utilized to determine an individual's zoxazolamine half-life which has been correlated with the genetically controlled level of benzo[a]pyrene hydroxylase induction. The latter measurement has been associated with risk to carcinoma. Thus, determination of the zoxazolamine half-life by means of the instant immunoassay can be used as a screening test for identifying individuals at special risk to cancer.

REFERENCES:
Conney et al., Fed. Proc., vol. 36, No. 5, Apr. 1977, pp. 1647-1652.

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