Immunoassay for N-desmethyldiazepam

Details Immunoassay for N-desmethyldiazepam Immunoassay for N-desmethyldiazepam

1978-04-07

1980-03-04

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

260112B, 2602393R, 424 12, 424 8, 23230B, G01N 3316, A61K 4300, A61K 3900, G21H 502

Patent

active

041917383

ABSTRACT:
Highly specific antibodies to N-desmethyldiazepam are obtained by using as an immunogen 4'-hydrazinocarbonylmethoxy-N-desmethyldiazepam coupled to an immunogenic carrier material such as bovine serum albumin. These antibodies can be employed in immunoassays for N-desmethyldiazepam which is a major metabolite of three important psychoactive drugs diazepam, chlordiazepoxide and clorazepate.

REFERENCES:
patent: 3966764 (1976-06-01), Goldstein et al.
patent: 4058511 (1977-11-01), Singh

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