Immunoassay for measurement of reticulocytes, and immunoreactive

Details Immunoassay for measurement of reticulocytes, and immunoreactive Immunoassay for measurement of reticulocytes, and immunoreactive

1980-04-09

1982-06-01

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 424 12, G01N 3356, G01N 3358

Patent

active

043327850

ABSTRACT:
The reticulocyte content present in a specimen of red blood cells is quantitatively measured based upon the selective immunoreactivity of the reticulocyte portion of the specimen with a reticulocyte-specific antibody which is immunoreactive with proteinaceous material associated with reticulocytes but not associated with mature red blood cells. Such immunoreactive proteinaceous material may be transferrin, transferrin receptor, transcobalamin II, or transcobalamin II receptor. Various procedures are described for quantitating such selective immunoreactivity, including fluorescent and radioactive detection techniques employing direct or indirect fluorescent or radioactive labeling of the reticulocyte-specific antibody.

REFERENCES:
patent: 4082085 (1978-04-01), Wardlaw et al.
patent: 4146604 (1979-03-01), Kleinerman
patent: 4273757 (1981-06-01), Selhub et al.

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