Immunoassay for human IgE

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 71, 435 72, 435 721, 435 724, 435 79, 435 792, 435 795, 43524027, 436501, 436506, 436513, 436518, 436811, 436804, 53038825, 53038873, 53038885, 5303911, 5303913, 530809, 530862, 530868, 935104, 935108, G01N 3353, G01N 33536, G01N 33543, G01N 33577

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055830056

ABSTRACT:
The present invention provides novel monoclonal antibodies HE-22A, HE-35A, HE-39E, and HE-69B against human IgE, a mixture thereof, hybridomas producing the antibodies, and immunoassays of human IgE employing the antibodies, which are useful for clinical diagnosis of allergic diseases or parasitic infections.

REFERENCES:
Nakamura et al., "Chapter 27", from: Handbook of Exp. Immunol., vol. 1: Immunochemistry, Ed. D. M. Weir et al., Blackwell Sci. Pub., 1986, pp. 27.1-27.20.
Toyoji Hozumi, Patent Abstracts of Japan, vol. 12, No. 398, p. 6 C 538, 1988.
Grassi et al., J. Allergy Clin. Immunol., vol. 77, No. 6, pp. 808-822 (1986).
Ichimori et al., Hybridoma, vol. 4, No. 1, pp. 47-53 (1985).
Anfosso et al., Molec. Immunol., 24(11), pp. 1129-1134 (1987).
Chretien et al., J. Immunol. 141, pp. 3128-3134 (1988).
Kornfeld et al, J. Biol. Chem., 250(7) pp. 2614-2619 (1975).

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