Immunoassay for HIV-I antigens using F(AB').sub.2 fragments as p

Details Immunoassay for HIV-I antigens using F(AB').sub.2 fragments as p Immunoassay for HIV-I antigens using F(AB').sub.2 fragments as p

1988-06-10

1991-01-08

Wax, Robert A.

Chemistry: analytical and immunological testing

Involving antibody fragments

435 5, 435 7, 436511, 436513, G01N 33563, C12Q 170, C12Q 100

Patent

active

049835297

ABSTRACT:
The present invention provides a probe for the detection of HIV 1 antigens, comprising anti-HIV 1 F(Ab').sub.2 fragments. The invention further provides an immunoassay with enhanced specificity.

REFERENCES:
patent: 4200436 (1980-04-01), Mochida et al.
patent: 4292403 (1981-09-01), Duermeyer
patent: 4298593 (1981-11-01), Ling
patent: 4722893 (1988-02-01), Shigeta et al.
patent: 4732848 (1988-03-01), Lenz et al.
patent: 4748110 (1988-05-01), Paul
P. Tijssen in: Practice and Theory of Enzyme Immunoassays, General Edits by Burdon & Knippenberg, Elsevier, 1985, pp. 117-119, 373-375.
Yolken, R. H. et al., "Enzyme Immunoassays for the Diagnosis of Viral Infections in: Defined Immunofluorescence & Related Cytochemical Methods Annals of the N.Y. Acad. Sci.", vol. 420: 381-390.

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