Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-07-21
1999-02-16
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4352521, G01N 33554, G01N 33569
Patent
active
058719423
ABSTRACT:
A process for the determination of H. pylori in a fecal specimen which comprises; (a) collecting a smear of a fecal specimen on a substrate; (b) immersing at least the portion of the substrate carrying the smear in a sample diluent so as to disperse the fecal specimen in the diluent; (c) contacting the fecal specimen in the diluent with a first polyclonal antibody for H. pylori antigen to form a complex of the antibody and the antigen; (d) separating the specimen and the complex; (e) exposing the complex to a second polyclonal antibody for the antigen and a portion of the antibody reacting with the complex, one of said first and second antibody being bound to a solid carrier and the other being labelled with a detection agent; and (f) determining the amount of the labelled antibody and in turn determining the presence of H. pylori antigen in the fecal specimen.
REFERENCES:
patent: 4882271 (1989-11-01), Evans et al.
patent: 4923801 (1990-05-01), Marshall et al.
patent: 4942126 (1990-07-01), Slifkin
patent: 5017342 (1991-05-01), Haberzettl et al.
patent: 5094956 (1992-03-01), Grow et al.
patent: 5262156 (1993-11-01), Alemohammad
patent: 5403924 (1995-04-01), Cover et al.
patent: 5420014 (1995-05-01), Cripps et al.
patent: 5478926 (1995-12-01), Nishimura et al.
patent: 5486361 (1996-01-01), Gralnick
patent: 5486452 (1996-01-01), Gordon et al.
patent: 5571674 (1996-11-01), Hoshina
patent: 5610060 (1997-03-01), Ward
patent: 5716791 (1998-02-01), Larka
Transmission of Helicobacter pylori via faeces, The Lancet, vol. 342, Dec. 4, 1993.
Enroth et al., J. Clin. Microbiol., Aug. 1995, 33(8), pp. 2162-2165.
Newell, D.G., J. Gen. Microbiol., 1987, vol. 133, pp. 163-170.
Kozak Kenneth James
Larka Christopher Vance
Yi Ching Sui Arthur
Housel James C.
Meridian Diagnostics, Inc.
Portner Ginny Allen
LandOfFree
Immunoassay for H. pylori in fecal specimens does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunoassay for H. pylori in fecal specimens, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunoassay for H. pylori in fecal specimens will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2061236