Immunoassay for estriol-3-sulfate

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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436529, 436538, 436543, 436547, 436808, 436817, 436822, 436825, 436826, 530403, 530404, 530405, 530406, 530807, G01N 33531, G01N 33537, G01N 33543, G01N 33548

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047404760

ABSTRACT:
A process for producing an antibody having a specificity to estriol-3-sulfate, which comprises administering a 6-substituted-estriol-3-sulfate protein conjugate of the formula: ##STR1## wherein A is .dbd.N--O-- or --O--CO--, n is an integer of 1 to 4 and --NH--P is the residue of a protein excluding a hydrogen atom in the amino form therefrom parenterally to a living body of a vertebrate animal so as to produce the antibody in the living body and collecting a body fluid comprising the antibody from the living body.

REFERENCES:
B. F. Erlanger, Meth. Enzmology, vol. 70, 85-104, 1980.
T. Nambara et al, J. Steroid Biochem., 21, 199-203, 1984.
T. Tanaka et al, Steroids, 43, 235-242, 1984.
T. Tanaka et al, Steroids, 46, 649-657, 1985.
T. Tanaka et al, J. Steroid Biochem., 22, 285-288, 1985.

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