Immunoassay for detecting group B streptococcus

Details Immunoassay for detecting group B streptococcus Immunoassay for detecting group B streptococcus

1991-04-25

1993-07-06

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 79, 435 794, 435 29, 435259, 435975, 435961, 5303884, 5303895, 5303911, 5303913, G01N 33569, C07K 1500, C07K 1528

Patent

active

052253317

ABSTRACT:
Immunoadsorbent combinations for the detection and diagnosis of group B streptococcus polysaccharide antigen, comprising an insoluble carrier, a capture agent having an affinity for specifically binding to the trirhamnose epitope of group B streptococcus antigen and having the formula .alpha.-L-Rhap(1.fwdarw.2)-.alpha.-L-Rhap(1.fwdarw.2).alpha.-Rhap- 1- wherein Rhap is rhamnose, and an antigen marker agent having an affinity for binding to monorhamnose epitope of group B streptococcus polysaccharide antigen of formula .alpha.-L-Rhap-1- when the group B streptococcus polysaccharide is bound to the carrier. An immunoassay method test kit and polyclonal antibody are also described.

REFERENCES:
Feldman et al, J. Clin. Pathol., 39:223-226 (1986).
Michon et al, Biochemistry, 27:5341-5351 (1988).
Wald et al, J. Clin. Microbiol., 25(3):573-574 (1987).

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