Immunoassay for creatine kinase-MB and creatine kinase-BB isofor

Details Immunoassay for creatine kinase-MB and creatine kinase-BB isofor Immunoassay for creatine kinase-MB and creatine kinase-BB isofor

1993-06-25

1995-01-17

Scheiner, Toni R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435 76, 435 792, 435 17, 435 26, 4351722, 43524027, 436524, 436528, 436811, 436815, 5303871, 5303881, 53038826, 5303893, G01N 33573, G01N 3353, C07K 1528

Patent

active

053825225

ABSTRACT:
Methods and reagents for determining the lapse of time since an acute disease event, such as the occurrence of a myocardial infarction, are presented. A serum or plasma sample is assayed to determine the concentration of two different analytes selected from the group consisting of creatine kinase-MB species and creatine kinase-BB species. From these measurements, the time of the acute event can be more accurately determined. Novel antibodies, labeled and insolubilized derivatives of these antibodies, labeled proteins, and kits containing one or more of these reagents are also described.

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