Immunoassay for catecholamines

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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23230B, 260112R, G01N 3316, A61K 4300

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active

041089731

ABSTRACT:
Epinephrine and norepinephrine type catecholamines can be individually assayed by immunoassay directed against the side chain common to these compounds by employing an oxidation procedure which selectively converts one or more of the epinephrine or norepinephrine type catecholamines to another compound which is not bound by the antibody. By measuring the difference between the total epinephrine or norepinephrine type catecholamine content and that after each of the oxidation steps, it is possible to determine the quantity of individual catecholamines of either type present in the original sample.

REFERENCES:
patent: 3704282 (1972-11-01), Spector
patent: 3878187 (1975-04-01), Schneider et al.
patent: 3996344 (1976-12-01), Gross
patent: 4016146 (1977-04-01), Soares

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