Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-01-04
2005-01-04
Chin, Christopher L. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007920, C435S070210, C435S452000, C435S327000, C435S337000, C435S965000, C435S975000, C436S518000, C436S528000, C436S548000, C530S387200, C530S388250, C530S391100
Reexamination Certificate
active
06838250
ABSTRACT:
The present invention relates to new CRP immunoassay compositions. The compositions include a low affinity anti-human CRP monoclonal antibody, and an antiidiotypic antibody raised against it. The invention further provides a method for obtaining antiidiotypic monoclonal antibody populations directed to an antibody that is specific for a high concentration, high molecular weight target antigen.
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patent: 5219730 (1993-06-01), Potocnjak et al.
patent: WO 9100872 (1991-01-01), None
J. Michael Kilpatrick et al., “Demonstration of Calcium-Induced Conformational Change(s) In C-Reactive Protein By Using Monoclonal Antibodies”, Molecular Immunology, 1982, pp. 1159-1165, vol. 19, No. 9, Pergamon Press Ltd., Great Britian.
Patrick Englebienne et al., “Water-Soluble Conductive Polymer Homogeneous Immunoassay (SOPHIA), A Novel Immunoassay Capable of Automation”, Journal Immunological Methods, 1996, pp. 159-170, vol. 191, APE Associates, Ghislenghien, Belgium.
Search Report of European Application No. EP 01303068, the European application corresponding to the parent application of the present case.
Daiss John L.
Scalice Edward R.
Antar Stacey B.
Chin Christopher L.
Grun James L.
Ortho-Clinical Diagnostics, Inc.
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