Immunoassay for analytes in samples using alkylating agents

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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Details

435 735, 435 737, 435962, 436825, G01N 33571, G01N 33569

Patent

active

054847060

ABSTRACT:
An improved immunoassay method and kit have been developed that include a sample pretreatment method and kit employing an alkylating agent that modifies antibodies in the sample to render the antibodies incapable of interfering with analyte detection. Prior to performing the immunoassay, the alkylating agent is inactivated so that it does not modify antibody reagents used in the immunoassay.

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