Chemical apparatus and process disinfecting – deodorizing – preser – Chemical reactor – Including plural reaction stages
Patent
1988-07-22
1992-10-06
Housel, James C.
Chemical apparatus and process disinfecting, deodorizing, preser
Chemical reactor
Including plural reaction stages
422 58, 136800, 136805, 136807, 136172, 356317, 2504591, 359 15, G01N 2100, G01N 2149
Patent
active
051529629
ABSTRACT:
An assay apparatus employing total internal reflection of excitation radiation at the interface between a replaceable optically conductive assay device and a surrounding liquid phase containing the substance being assayed. The assay device is formed of a radiation transmissive, elongated fiber having on the surface thereof a component of a complex formed in an immunological-type specific reaction. A fluorophore that can be excited into fluorescence by the excitation radiation is attached to another component of the complex. The assay device also includes a boss formed of a similarly radiation transmissive material with an index of refraction preferably matched to that of the fiber, one end of the fiber being fixedly coupled to the boss. The boss is dimensioned so that the maximum solid acceptance angle for excitation radiation introduced into the fiber end lies totally within the transmissive medium of said boss. In one embodiment, the fiber is coaxially mounted within a tube that is sized with respect to the fiber so that a fluid sample may be introduced into the tube.
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patent: 4321057 (1982-03-01), Buckles
patent: 4399099 (1983-08-01), Buckles
patent: 4447546 (1984-05-01), Hirschfeld
patent: 4671938 (1987-06-01), Cook
patent: 4844869 (1989-08-01), Glass
Alexander Lyle
Housel James C.
ORD Corp.
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