Immunoadsorbent polymeric material and method of making same

Details Immunoadsorbent polymeric material and method of making same Immunoadsorbent polymeric material and method of making same

1976-07-02

1978-01-17

Serwin, R.E.

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

23230B, 23253TP, 23259, 1951035A, 424 1, 424 12, G01N 3316, G01T 116

Patent

active

040693520

ABSTRACT:
Gamma globulins from antisera having a titer so low in selected antibodies that the antibodies adsorbed on a surface of polymeric material are ineffective for use in immunoassay, are cross-linked, then adsorbed on the polymeric surface to provide an immunologically active coating. Binding proteins incapable of effective adsorption on polymeric surfaces are cross-linked with gamma globulin, then adsorbed on a surface of polymeric material capable of adsorbing gamma globulin to provide a specific binding protein coating. Kits containing test tubes having such coatings are used in radioimmunoassay, in enzyme immunoassay, and in fluoroimmunoassay.

REFERENCES:
patent: 3646346 (1972-02-01), Catt
patent: 3826619 (1974-07-01), Bratu, Jr. et al.
patent: 3980764 (1976-09-01), Adams
patent: 3995019 (1976-11-01), Jerome
patent: 4012494 (1977-03-01), Ling

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