Immuno-suppressive agents

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424318, 424195, 424 85, A61K 3123, A61K 3120

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active

039937755

ABSTRACT:
A method of providing an immuno-suppressive effect in the control or prophylaxis of neurological disorders, such as multiple sclerosis, and in organ and tissue transplants comprising administering a daily dosage of 5mg to 3g of .gamma.-linolenic or dihomo-.gamma.-linolenic acid or a functional derivative thereof, optionally together with a daily dosage of 25mg to 3g of linoleic acid or a functional derivative thereof. An oil extract from seeds of Oenothera biennis L. is a convenient source of .gamma.-linolenic acid and linoleic acid.

REFERENCES:
patent: 3163639 (1964-12-01), Hitchings et al.
patent: 3676472 (1972-07-01), Zilliken et al.
Advan. Lipid Res. 1972, 10, 43-88.
E. F. Steinmetz "Codex Vegetabilis", item 768.

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