Immunization against infection by Escherichia coli

Details Immunization against infection by Escherichia coli Immunization against infection by Escherichia coli

1982-09-13

1984-06-12

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

A61K 39108, A61K 3902

Patent

active

044541171

ABSTRACT:
There is provided a vaccine material capable of providing substantial levels of protection against human disease caused by infection with Escherichia coli. The protecting means comprises pili of the infecting organism. The protection is given either by administering the pili directly to the subject to be protected or to a pregnant or lactating female where protection of the newborn is desired.

REFERENCES:
patent: 4237115 (1980-12-01), Brinton
Brinton, Nature, vol. 183, Mar. 21, 1959, pp. 782-786.
Brinton, Biochim Biophys Acta, vol. 42, 1960, pp. 298-311.
Brinton, Trans. NY Acd. Sci., Ser. II, vol. 27, Jun. 1965, pp. 1003-1053.
Morgan, Inf. & Immunity, vol. 22, 1978, pp. 771-777.

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