Immune system stabilizers for prevention and therapy of disorder

Drug – bio-affecting and body treating compositions – Lymphokine

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424 88, A61K 3900

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active

052308871

ABSTRACT:
Substances that bind to alloimmune-immunogen-absorbed (AIA) sera have been found to be effective in the prevention and therapy of autoimmune disease. It is conjectured that the mechanism involves indirect stimulation of suppressor T cells resulting in stabilization of the immune system. The administration of such substances is expected to be useful in the prevention and treatment of diseases that involve a failure of the immune system to distinguish adequately between self and nonself, including autoimmune diseases and immunodeficiency diseases.

REFERENCES:
patent: 4719107 (1988-01-01), Carosella et al.
patent: 4966753 (1990-10-01), McMichael
patent: 5004604 (1991-04-01), Terness et al.
Golding et al., Chem. Abstracts (1988) 108(23):534 (Abstract No. 203058w.
Schrier et al., J. Immunol. (1989) 142(4):1166-1176.
Hoffmann et al., Proc. Natl. Acad. Sci. (1991) 883060-883064.
Sinha, et al., 1990, "Autoimmune Diseases: The Failure of Self Tolerance," Nature 248: 1380-1387.
Hoffmann, et al., 1986, "A new symmetry: A anti-B is anti-(B anti-A), . . . " J. Immunol. 137(1): 61-8.
Shearer, Mount Sinai J. Med. (1986) 53(8):609-615.
Andrieu et al., AIDS Research (1986) 2(3):163-174.
Martinez et al., Lancet (1988) I(8583):454-456.
Siliciano et al., Cell (1988) 54:561-575.
Hoffmann The Semiotics of Cellular Communication in the Ummune System, Sercarz, E. E. et al., eds. (1988) Springer Verlag, pp. 257-271.
Lanzavecchia Research in Immunology (1989) 140:99-103.
Calabrese, Clin. Lab. Med. (1988) 8:269-279.
Habeshaw et al., J. Acqu. Imm. Def. (1989) 2(5):457-468.
Morrow et al., Clin. Immunol. and Immunopath. (1990) 57:in press.
Grant et al., Cellular Basis of Immune Modulation Caplan J. G. et al., eds., (1989) A. R. Liss, Inc., New York, pp. 481-484.
Hoffmann et al., Canadian Research (1988) 21:16-23.
Grant et al., J. Immunol. (1990) 144(4):1241-1250.
Hoffman et al., "Mathematical and Statistical Approaches to AIDS Epidemiology", Castillo-Chavez ed., Lect. Notes in Biomat. (1989) 83:386-405.
Hoffmann et al., "Idiotype Networks in Biology and Medicine" Osterhaus et al., eds., (1990) Elsevier, Amsterdam, pp. 295-299.
Hoffmann et al., Immunology Letters (1989) 22:83-90.
Hoffmann et al., Theoretical Immunology A. S. Perelson, ed. Addison-Wesley, Redwood City, Calif. (1988) pp. 291-319.
Cohen Sci. Amer. (1988) 258:34-42.
Shearer et al., Annals N.Y. Acad. Sci. (1985) 437:49-57.
Ziegler et al, Clin. Immunol. and Immunopathol. (1986) 41:305-313.
Elkins, et al., 1987 "Prior exposure to subimmunogenic amounts . . . " Infect. & Imm. 55:3085-3092.
Klasse et al., 1988 "Presence of antibodies to a putatively . . . " PNAS 55; 5225-5229.
Kion and Hoffmann, Science 253:1138-1140 (1991).

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