Immune response to virus induced by anti-idiotype antibodies

Drug – bio-affecting and body treating compositions – Lymphokine

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4351722, 43524027, 935 95, 935104, 935107, A61K 3942, C12N 1500, C12N 500

Patent

active

047312378

ABSTRACT:
A method of inducing an immunological response in a host to a virus is provided employing anti-idiotype antibodies that present an internal image of a viral antigen to the host. Anti-idiotype antibodies and the cell lines that produce such antibodies are also provided.

REFERENCES:
patent: 4172124 (1979-10-01), Koprowski
patent: 4196265 (1980-04-01), Koprowski
Chemical Abstracts, vol. 97, 179920c, 1982.
Chemical Abstracts, vol. 100, 207644c, 1984.
Chemical Abstracts, vol. 100, 83892z, 1984.
Chemical Abstracts, vol. 101, 108793d, 1984.
Herlyn et al., "Colorectal Carcinoma-Specific Antigen: Detection by Means of Monoclonal Antibodies," Proc. Natl. Acad. Sci. USA 76, pp. 1438-1442, 1979.
Stevenson et al., "Treatment of Lymphoid Tumors with Anti-Idiotype Antibodies," Springer Seminars in Immunopathology 6, pp. 99-115, 1983.
Kozbor et al., "Human Hybridomas Constructed with Antigen-Specific Epstein-Barr Virus-Transformed Cell Lines," Proc. Natl. Acad. Sci. USA, vol. 79, pp. 6651-6655, 1982.
Haughton et al., "Antigen-Induced Murine B Cell Lymphomas II. Exploitation of the Surface Idiotype as Tumor Specific Antigen," The Journal of Immunology, vol. 121, No. 6, pp. 2358-2362, 1978.
Thielemans et al., "Strategies for Production of Monoclonal Anti-Idiotype Antibodies Against Human B Cell Lymphomas," The Journal of Immunology, vol. 133, No. 1, pp. 495-501, 1984.
Kim et al., "Polyvalent Epitope Inhibits but Added with Anti-Idiotype Antibody Enhances Idiotype Suppression," The Journal of Immunology, vol. 131, No. 1, pp. 13-15, 1983.
Forstrom et al., "Immunization to a Syngeneic Sarcoma by a Monoclonal Auto-Anti-Idiotypic Antibody", Nature, vol. 303, pp. 627-629, 1983.
Gheuens et al., "Idiotypes and Biological Activity of Murine Monoclonal Antibodies Against the Hemagglutinin of Measles Virus," Infection and Immunity, vol. 34, No. 1, pp. 200-207, 1981.
Metzger, "A Mouse Monoclonal Antibody Against Rabbit V.sub.H Allotype Shares the Predominant Idiotype with a Rabbit Antibody of the Same Specificity," Eur. J. Immunol., vol. 14, pp. 304-308, 1984.
Kauffman et al., "Cell Receptors for the Mammalian Reovirus II. Monoclonal Anti-Idiotypic Antibody Blocks Viral Binding to Cells," J. of Immunology, vol. 131, No. 5, pp. 2539-2541, 1983.
Noseworthy et al., "Cell Receptors for the Mammalian Reovirus I. Syngeneic Monoclonal Anti-Idiotypic Antibody Identifies a Cell Surface Receptor for Reovirus," J. of Immunology, vol. 131, No. 5, pp. 2533-2538, 1983.
Ionescu-Matiu et al., "Epitopes Associated with a Synthetic Hepatitis B Surface Antigen Peptide," J. of Immunology, vol. 130, No. 4, pp. 1947-1952, 1983.
Kennedy et al., "Inhibition of a Common Human Anti-Hepatitis B Surface Antigen Idiotype by a Cyclic Synthetic Peptide," Journal of Virology, vol. 46, No. 2, pp. 653-655, 1983.
Urbain, Springer Seminars in Immunopathology, vol. 6, pp. 1-5, 1983.
Eichmann et al., "Network Regulation Among T Cells; Conclusions from Limiting Dilution Experiments," Springer Seminars in Immunopathology, vol. 6, pp. 7-32, 1983.
Goldman et al., "Pathological Expression of Idiotypic Interactions: Immune Complexes and Cryoglobulins," Springer Seminars in Immunopathology, vol. 6, pp. 33-49, 1983.
Roitt et al., "Idiotypes and Autoimmunity", Springer Seminars in Immunopathology, vol. 6, pp. 51-66, 1983.
Strosberg, "Anti-Idiotype and Anti-Hormone Receptor Antibodies," Springer Seminars in Immunopathology, vol. 6, pp. 67-78, 1983.
Rodkey, "Autoregulation of Immune Responses via Idiotype Network Interactions," Microbiological Reviews, vol. 44, pp. 631-659, 1980.
Nisonoff et al., "Hypothesis Implications of the Presence of an Internal Image of the Antigen in Anti-Idiotypic Antibodies: Possible Application to Vaccine Production," Clinical Immunology and Immunopathology, vol. 21, pp. 397-406, 1981.
Sacks et al., "Induction of Immune Responses with Anti-Idiotypic Antibodies: Implications for the Induction of Protective Immunity," Springer Seminars in Immunopathology, vol. 6, pp. 79-97, 1983.
Reagan et al., "Anti-Idiotypic Antibodies Induce Neutralizing Antibodies to Rabies Virus Glycoprotein," Journal of Virology, vol. 48, pp. 660-666, 1983.
Koprowski et al., "Human Anti-Idiotype Antibodies in Cancer Patients; Is the Modulation of the Immune Response Beneficial for the Patient?", Proc. Natl. Acad. Sci. USA, vol. 81, pp. 216-219, 1984.
Kennedy et al., (1984) J. Exp. Med. 159:655-665.
Kennedy et al., (Aug. 1983) Science 221:853-855.
Kennedy et al., (1984) J. Virol. 50:951-953.
Sacks et al., (1982) J. Exp. Med. 155:1108-1119.
Nepom et al. (1984) Proc. Natl. Acad. Sci. USA 81:2864-2867.
Eichmann et al., (1975) Eur. J. of Immunol. 5:661-666.
Geha, (1981), N. Engl. J. Med. 305:25-28.
Eichmann, (1974) Eur. J. of Immunol. 4:296-301.
Bona et al., (1981) J. Exp. Med. 153:951-967.
Sege et al. (1978) Proc. Natl. Acad. Sci USA 75:2443-2447.
Nepom et al. (1982) J. Exp. Med. 155:155-167.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Immune response to virus induced by anti-idiotype antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immune response to virus induced by anti-idiotype antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immune response to virus induced by anti-idiotype antibodies will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1925692

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.