Immune reactivity to expressed activated oncogenes for diagnosis

Details Immune reactivity to expressed activated oncogenes for diagnosis Immune reactivity to expressed activated oncogenes for diagnosis

1992-01-13

1994-06-14

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 71, 435 723, 4352401, 4352402, 424520, 530351, 530395, C07K 300, C12Q 100, C12N 500, A01N 6300

Patent

active

053209478

ABSTRACT:
Methods for the detection, monitoring and treatment of malignancies are disclosed. Detection of the proliferation of T cells in response to in vitro exposure to a protein expression product of an activated oncogene or cancer-related gene associated with a malignancy, or detection of immunocomplexes formed between the protein expression product and antibodies in body fluid, allows the diagnosis of the presence of a malignancy. The present invention also discloses methods and compositions for treating a malignancy.

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