Immune mediators and related methods

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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530350, 5303871, 5303882, 53038822, 53038875, 5303896, 5303911, C12N 506, C07K 1628, C07K 1714

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active

060603097

ABSTRACT:
A method for preparing a responder cell clone that proliferates when combined with a selected antigenic peptide presented by a stimulator cell is disclosed. CD56 negative, CD8 negative responder cells are isolated from peripheral blood mononucleocytes and stimulated with pulsed or primed stimulator cells. Responder cell clones from prediabetic or new onset diabetic patients which are specific for GAD peptides are also disclosed.

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