Immune complex assay

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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23230B, 424 8, 424 78, 424 85, 424 88, G01N 3350, G01N 3354, G01N 3368

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active

043316492

ABSTRACT:
Method for the estimation of immune complex and analysis of a constituent thereof. Method comprises a latex particle agglutination test in which a reagent comprising low affinity latex particles is contacted with a sample containing immune complex. The low affinity coated latex particles are latex particles coated with IgG antibodies to the complex constituent and may be prepared by contacting latex particles with the IgG antibodies, the latter optionally being substituted with a coupling agent. One or more reagents are conveniently provided in kit form.

REFERENCES:
patent: 3088875 (1963-05-01), Fisk
patent: 4118349 (1978-10-01), Bonacker
patent: 4141965 (1979-02-01), Soothill
patent: 4181636 (1980-01-01), Fischer
Chantler, J. Immunol. Methods, vol. 13, 1976, pp. 367-380.

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