Immortalized preosteoblasts and method for their production

Details Immortalized preosteoblasts and method for their production Immortalized preosteoblasts and method for their production

2007-04-10

2007-04-10

Nguyen, Quang (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

C435S455000, C435S004000

Reexamination Certificate

active

10422996

ABSTRACT:
The present invention relates to novel immortalized pre-osteoblast cell lines derived from the periost and capable of differentiate to osteoblasts. In particular, the present invention pertains to the use of such cell lines in assays for detecting substances controlling the differentiation of pre-osteoblasts to osteoblasts and for detecting substances enabling improved bone formation, maintenance of bone mass, bone repair and for preventing the onset of osteoporosis.

REFERENCES:
patent: 6399384 (2002-06-01), Jat
patent: WO/93 23572 (1993-11-01), None
patent: WO/95 02687 (1995-01-01), None
patent: WO/95 13383 (1995-05-01), None
patent: WO/99 39724 (1999-08-01), None
patent: WO/01 21790 (2001-03-01), None

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