Immortalized human fetal osteoblastic cells

Details Immortalized human fetal osteoblastic cells Immortalized human fetal osteoblastic cells

1993-07-12

1997-11-25

Fleisher, Mindy

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4352402, C12N 1564, C12N 510

Patent

active

056911750

ABSTRACT:
Immortalized normal human fetal osteoblastic cells that express a temperature sensitive mutant of simian virus 40 large T antigen are provided.

REFERENCES:
patent: 5028425 (1991-07-01), Good et al.
Price et al., Eur. J. Clin. Nutr., vol. 48, Suppl. 1, 1994, pp. S131-S149.
Pfeilschifter et al., Endocrinology,vol. 127, 1990, pp. 69-75.
Quarles, Miner. Electrolyte Metab., vol. 17, 1991, pp. 233-239.
Bodo et al., Cell. Mol. Biol., vol. 37, 1991, pp. 597-606.
T.K. Gray et al., "Estradiol Stimulates in vitro the Secretion of Insulin-like Growth Factors by the Clonal Osteoblastic Cell Line, UMR106", Bioc. Biophys. Res. Comm., 158, 407-412 (1989).
P.J. Greenaway et al., "Human cytomegalovirus DNA: BamHi, EcoRI and PstI restriction endonuclease cleavage maps", Gene, 18, 355-360 (1982).
R.G. Ham et al., "Media and Growth Requirements", Methods Enzymol., 58, 44-93 (1979).
S.A. Harris et al., "Estrogen Induces C-FOS Promoter Activity in Normal Human Osteoblast-Like Cells", J. Bone Min. Res., 7, Abstract No. 7 (1992).
S.A. Harris et al., "Development and Characterization of a Conditionally Immortilized Human Fetal Osteoblastic Cell Line", J. Bone Min. Res., 1-14 (1993).
S.A. Harris et al., "Development and Characterization of a Conditionally-Transformed Human Fetal Osteoblastic Cell Line", J. Bone Min. Res., 8, S303, Abstract No. 745 (1993).
R.L. Jilka et al., "Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6", Science, 257, 88-91 (Jul. 3, 1992).
K.J. Kaneko et al., "Activation of the Silent Progesterone Receptor Gene by Ectopic Expression of Estrogen Receptors in a Rat Fibroblast Cell Line", Biochemistry, 32, 8348-8359 (1993).
B.S. Komm, "Estrogen Binding, Receptor mRNA, and Biologic Response in Osteoblast-Like Osteosarcoma Cells", Science, 241, 81-84 (Jul. 1, 1988).
Y. Liel et al, "Evidence That Estrogens Modulate Activity and Increase the Number of 1,25-Dihydroxyvitamin D Receptors in Osteoblast-Like Cells (ROS 17/2.8)", Endocrinology, 130, 2597-2601 (1992).
R. Lindsay, "The influence of cigarette smoking on bone mass and bone loss", Osteoporosis: Recent Advances in Pathogenesis and Treatment; University Park Press: Baltimore, MD; 481 (1981).
A.M. Maxam et al., "Sequencing End-Labeled DNA with Base-Specific Chemical Cleavages", Methods Enzymol., 65, 499-560 (1980).
G.K. McMaster et al, "Analysis of single-and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange", Proc. Natl. Acad. Sci. USA, 74, 4835-4838 (Nov. 1977).
J. Messing et al., "A system for shotgun DNA sequencing", Nucl. Acids Res., 9, 309-320 (1981).
R.C. Mulligan et al., "Expression of a Bacterial Gene in Mammalian Cells", Science, 209, 1422-1427 (1980).
M.J. Oursler et al, "Modulation of Transforming Growth Factor-.beta. Production in Normal Human Osteoblast-Like Cells by 17.beta.-Estradiol and Parathyroid Hormone", Endocrinology, 129, 3313-3320 (1991).
R. Pacifici et al., "Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release", Proc. Natl. Acad. Sci. USA, 86, 2398-2402 (Apr. 1989).
G. Passeri et al., "Increased Interleukin-6 Production by Murine Bone Marrow and Bone Cells after Estrogen Withdrawal", Endocrinology, 133, 822-828 (1993).
G.N. Pavlakis et al., "Expression of two human growth hormone genes in monkey cells infected by simian virus 40 recombinants", Proc. Natl. Acad. Sci. USA, 7, 7398-7402 (Dec. 1981).
B.L. Riggs et al., "Short-and Long-Term Effects of Estrogen and Synthetic Anabolic Hormone in Postmenopausal Osteoporosis", J. Clin. Investigation, 51, (Jul. 1972).
P. Sassone-Corsi et al., "Transcriptional autoregulation of the proto-oncogene fos", Nature, 334, 314-319 (Jul. 1988).
B. Sugden et al., "A Vector That Replicates as a Plasmid and Can be Efficiently Selected in B-Lymphoblasts Transformed by Epstein-Barr Virus" Mol. Cell. Biol., 5, 410-413 (Feb. 1985).
S.N. Thibodeau et al., "Simultaneous Measurement of Estrogen and Progesterone Receptors in Tumor Cytosols with Use of .sup.125 I-Labeled Estradiol and of .sup.3 H-R5020", Clin. Chem., 27, 687-691 (1981).
D.R. Thomsen, "Promoter-regulatory region of the major immediate early gene of human cytomegalovirus", Proc. Natl. Acad. Sci. USA, 81, 659-663 (Feb. 1984).
L. Tora et al., "The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties", EMBO J., 8, 1981-1986 (1989).
A. Weisz et al., "Estrogen Induces Expression of c-fos and c-myc Protooncogenes in Rat Uterus", Mol. Endocrinol., 2, 816-824 (Sep. 1988).
A. Weisz et al., "Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factor", Nucl. Acids Res., 18, 5097-5106 (1990).
G. Wilding et al., "Effects of Steroid Hormones and Peptide Growth Factors on Protooncogene c-fos Expression in Human Breast Cancer Cells", Cancer Res., 48, 802-805 (Feb. 15, 1988).
Current Protocols in Molecular Biology; Eds., F.M. Ausubel et al., Eds, John Wiley & Sons: New York, NY; 1989. Enclosed is the Title page, Copyright page and Contents pages (pp. iii-x).
D. Barnes et al., "Methods for Growth of Cultured Cells in Serum-Free Medium", Anal. Biochem., 102, 255-270 (1980).
S.K. Chattopadhyay et al., "Quantitative studies of integration of murine leukemia virus after exogenous infection", Proc. Natl. Acad. Sci. USA, 73, 4095-4099 (1976).
P. Chomczynski, "A Reagent for the Single-Step Simultaneous Isolation of RNA, DNA and Proteins from Cell and Tissue Samples", BioTechniques, 15, 532-536 (1993).
D.S. Colvard et al., "Microassay for Nuclear Binding of Steroid Receptors with Use of Intact Cells from Small Samples of Avian and Human Tissue", Clin. Chem., 34, 363-369 (1988).
E.F. Eriksen et al., "Evidence of Estrogen Receptors in Normal Human Osteoblast-Like Cells", Science, 241, 84-86 (Jul. 1, 1988).
M. Ernst et al., "Estradiol Effects on Proliferation, Messenger Ribonucleic Acid for Collagen and Insulin-like Growth Factor-I, and Parathyroid Hormone-Stimulated Adenylate Cyclase Activity in Osteoblastic Cells from Calvariae and Long Bones", Endocrinology, 125, 825-833 (1989).
M.C. Etienne et al., "Steroid Receptors in Human Osteoblast-like Cells", Eur. J. Cancer, 26, 807-810 (1990).
W. Fiers et al., "Complete nucleotide sequence of SV40 DNA", Nature, 273, 113-120 (May 11, 1978).
T.K. Gray et al., "17.beta.-Estradiol acts directly on the clonal osteoblastic cell line UMR106", Proc. Natl. Acad. Sci., 84, 6267-6274 (1987).
T.C. Spelsberg, "Bone Cell Proto-Oncogene Promoters", National Institute of Health Grant No. AR41652.
T.C. Spelsberg, "Sex Steroids, Growth Factors and Bone Cell Function", National Institute of Health Grant No. AG04875.
M. Bodo et al., "Effects of Steroids on Human Normal and Otosclerotic Osteoblastic Cells: Influence on thymidine and Leucine Uptake and Incorporation," Cell. Mol. Biol., 37, 597-606 (1991).
E. Canalis et al., "Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures," J. Clin. Invest., 83, 60-65 (Jan. 1989).
S.A. Harris et al., "Development and Characterization of a Conditionally Immortalized Human Fetal Osteoblastic Cell Line," J. of Bone and Min. Res., 10, 178 (1995).
T. Katagiri et al., "The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2," Biochem. Biophys. Res. Comm., 172, 295-299 (Oct. 15, 1990).
T. Katagiri et al., "Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage," J. Cell Biol., 127, 1755-1766 (Dec., 1994).
C. Liu et al., "Human parathyroid hormone-(1-34) prevents bone loss and augments bone formation in sexually mature overiectomized rats," J. Bone Miner. Res., 5, 973-982 (1990).
C. Marcelli et al., "In vivo effects of human recombinant transforming growth factor beta on bone turnover in normal mice," J. Bone Miner. Res., 5, 1087-1096 (1990).
T.M. Murray et al., "Human parathyroid hormone carboxyterminal peptide (53-84) stimulates alka

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