Immortalized human cell lines containing exogenous cytochrome P4

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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435 691, 4351722, C12N 510

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053568060

ABSTRACT:
Non-tumorigenic, human bronchial epithelial cell lines are provided wherein the cell lines are capable of expressing cytochrome P450 genes which have been inserted into the cell lines. Also provided are methods and kits for identifying potential mutagens, cytotoxins, carcinogens, and chemotherapeutic agents utilizing these cell lines.

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