Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1992-02-21
1995-07-11
Elliott, George C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
4352402, C12Q 102, C12N 508
Patent
active
054320607
ABSTRACT:
Human bronchial epithelial cell lines permanently transformed by human papilloma viruses have been obtained. These cell lines are useful for the study of growth and differentiation in bronchial carcinoma and the identification of chemical and biological agents that may be useful in the therapy of human lung cancer.
REFERENCES:
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Pecoraro, et al. Differential Effects of Human Papilloma Virus Type 6, 16, and 18 DNAs on Immortalization and Transformation . . . Proc. Natl. Acad. Sci. (USA) vol. 86 pp. 563-567 Jan., 1989.
Band, et al. Human Papilloma virus DNAs Immortalize Normal Human Mammary Epithelial Cells and Reduce Their Growth Factor Requirements Proc. Natl. Acad. Sci. (USA) vol. 87 pp. 463-467 Jan., 1990.
Ostrow, et al. A Survey of Human Cancers For Human Papillomavirus DNA by Filter Hybridization Cancer (USA) vol. 59 No. 3 pp. 429-434 (Abstract) 1987.
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Pecoraro et al, PNAS, USA. 86:563-567, 1989.
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Band, et al, PNAS, USA. 87:463-467, 1990.
Stoner et al, Abstract, Proc. AACR, 30:218, 1989.
Lechner, et al., "In Vitro Human Bronchial Epithelial Model Systems for Carcinogenesis Studies", In Vitro Models for Cancer Research, vol. VI, Chapter 1, 1983, pp. 3-17.
Pirisi, et al., "Continuous Cell Lines with Altered Growth and Differentiation Properties Originate After Transfection of Human Keratinocytes with Human Papillomavirus type 16 DNA", Carcinogenesis, vol. 9, No. 9 1988, pp. 1573-1579.
Harris Curtis C.
Willey James C.
Elliott George C.
The United States of America as represented by the Secretary of
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