Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Recovery or purification
Patent
1998-09-11
1999-11-16
Ketter, James
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Recovery or purification
435349, 435455, C12N 702
Patent
active
059856424
ABSTRACT:
This invention relates to the production and use of immortalized cell lines from primary chicken embryonic fibroblasts. The cells are useful as substrates for virus propagation, recombinant protein expression and recombinant virus production.
REFERENCES:
Givol et al., "Overexpression of human p21.sup.waf1/cip1 arrests the growth of chicken embryo fibroblasts transformed by individual oncogenes", Oncogene, 11(12) 2609-2618 (1995).
Givol et al., "Bcl-2 Expressed Using a Retroviral Vector Is Localized Primarily in the Nuclear Membrane and the Endoplamic Reticulum of Chicken Embryo Fibroblasts.sup.1 ", Cell Growth & Differentiations, 5(4) 419-429 (1994).
Hamburger et al., "Soft-Agar Cloning of Cells From Patients With Lymphoma", Prog. Clin. Biol. Res., Cloning of Human Tumor Stem Cells, 48 43-52 (1980).
Harvey et al., "p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts", Genes and Development, 5 2375-2385 (1991).
M. Hill et al., "Isolation of a Line of Immortal Chicken Embryo Fibroblasts after Transfection with Nuclei of Rous Sarcoma Virustransformed Chinese Hamster Cells", Experimental Cell Research, 156, 127-139 (1985).
B. Kressner et al., "Use of an Image Analysis System to Count Colonies in Stem Cell Assays of Human Tumors", Prog. Clin. Biol. Res., Cloning of Human Tumor Stem Cells, 48 179-193 (1980).
Pereira-Smith et al., "Genetic analysis of indefinite division in human cells: Identification of four complementation groups", Proc. Natl. Acad. Sci. USA, 85 6042-6046 (1988).
Pereira-Smith et al., "Hybrids From Fusion of Normal Human T Lymphocytes With Immortal Human Cells Exhibit Limited Life Span", J. Cell Physiol., 144 546-549 (1990).
S. Salmon, "Morphologic Studies of Tumor Colonies", Prog. Clin. Biol. Res., Cloning of Human Tumor Stem Cells, 48 135-151 (1980).
Smith et al., "Replicative Senescence: Implications for in Vivo Aging and Tumor Suppression", Science, 273 63-67 (1996).
C.F. Boerkoel et al., "A New Defective Retroviral Vector System Based on the Bryan Strain of Rous Sarcoma Virus", Virology, 195(2) 669-679 (1993).
Boyer et al., "Sequence and biological activity of chicken snoN cDNA clones", Oncogene, 8 457-466 (1993).
L.B. Crittenden et al., "Host Gene Control of Endogenous Avian Leukosis Virus Production", Virology, 57 128-138 (1974).
L. Curatolo et al., "Culture Conditions Induce the Appearance of Immortalized C.sub.3 H Mouse Cell Lines", In Vitro, 20 597-601 (1984).
Federspiel et al., "Effects of the gag Region on Genome Stability: Avian Retroviral Vectors That Contain Sequences from the Bryan Strain of Rous Sarcoma Virus.sup.1 ", Virology, 203(2) 211-220 (1994).
Foster et al., "Immortalization of Chicken Embryo Fibroblastic Cells", 84.sup.th Annual Meeting of the Poultry Science Assoc., Inc., Edmonton, Alberta, Canada, Aug. 14-18, 1995, 74 (Suppl. 1) 1995.
Foster Douglas N.
Foster Linda K.
Ketter James
Regents of University of Minnesota
Yucel Irem
LandOfFree
Immortalized cell lines for virus growth does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immortalized cell lines for virus growth, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immortalized cell lines for virus growth will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1323518