Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Reexamination Certificate
2006-01-03
2006-01-03
Ungar, Susan (Department: 1642)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
C435S366000, C435S371000, C435S384000, C435S385000, C435S386000
Reexamination Certificate
active
06982168
ABSTRACT:
The present invention relates to immortalized, malignant, human, adult prostate epithelial cell lines or cell lines derived therefrom useful in the diagnosis and treatment of prostate cancer. More particularly, the present invention relates to cloned, immortalized, malignant, human, adult prostate epithelial cell lines and uses of these cell lines for the diagnosis and treatment of cancer. Furthermore, the present invention provides for the characterization of said cell lines through the analysis of specific chromosomal deletions.
REFERENCES:
patent: 5026637 (1991-06-01), Soule et al.
patent: 5376542 (1994-12-01), Schlegal
patent: 5436152 (1995-07-01), Soule et al.
patent: 5443954 (1995-08-01), Reddel et al.
patent: 5462870 (1995-10-01), Chopra
patent: 5576206 (1996-11-01), Schlegel
patent: 5716830 (1998-02-01), Webber et al.
patent: 5824488 (1998-10-01), Webber et al.
patent: WO 92/16645 (1992-10-01), None
patent: WO 95/29990 (1995-11-01), None
patent: WO 95/29994 (1995-11-01), None
Chiarello, E, Oncogene 16: 541-545, 1998.
Kelemen. Genes Chromosomes Cancer 11:195-198, 1994.
Drexler. Leukemia & Lymphoma 9:1-25, 1993.
Embleton, Immunol. Ser. 23:181-207, 1984.
Heu, In: Tissue Culture Meth & Applications, Kruse & Patterson, Eds, p. 764, 1973.
Mustafa O. Intl. J. Oncol. 8(5):883-888, 1996.
ATCC Catalogue of Cell Lines & Hybridomas, 6th edition, pp. 145 and 222, 1988.
Bernardino et al. “Characterization of Chromosome changes in two human prostatic charcinoma cell lines (PC-3 and DU 145) using chromosome painting and comparative genomic hybridization” Cancer Genet. Cytogenet. vol. 96, pp. 123-128, 1997.
Freshney, Culture of Animal Cells, A manual of basic technique chapter 13, p. 130, 1983.
Smith, R. T. “Cancer and the immune system” Clinical Immunology. vol. 41 No. 4, pp. 841-850, Aug. 1994.
McInerney J. M et al. Gene Therapy 7(8): 653-63, 2000.
Parda et al, “Neoplastic Transformation of a Human Prostate Epithelial Cell Line by the v-Ki-ras Oncogene”,The Prostate23:91-98 (1993).
Hayward et al, “Establishment and Characterization of an Immortalized But Non-Transformed Human Prostate Epithelial Cell Line: BPH-1”,In Vitro Cell Dev. Biol. 31A:14-24, Jan. 1995.
Castagnetta et al, “Prostate Long-Term Epithelial Cell Lines”,Annals of The New York Academy of Sciences, vol. 595, pp. 149-164, 1990.
Boudou et al, “Distinct Androgen 5a-Reduction Pathways in Cultured Fibroblasts and Immortalized Epithelial Cells From Normal Human Adult Prostate”,The Journal of Urology, vol. 152, 226-231, Jul. 1994.
Narayan et al, “Establishment and Characterization of a Human Primary Prostatic Adenocarcinoma Cell Line (ND-1)”,The Journal of Urology, vol. 148, 1600-1604, Nov. 1992.
Rhim et al, “Stepwise immortalization and transformation of adult human prostate epithelial cells by a combination of HPV-18 and v-Ki-ras”,Proc. Natl. Acad. Sci. USA, vol. 91, pp. 11874-11878, Dec. 1994.
Cussenot et al, “Immortalization of Human Adult Normal Prostatic Epithelial Cells By Liposomes Containing Large T-SV40 Gene”,The Journal of Urology, vol. 143, 881-886, Sep. 1991.
Weijerman et al, “Lipofection-mediated Immortalization of Human Prostate Epithelial Cells of Normal and Malignant Origin Using Human Papillomavirus Type 18 DNA1”,Cancer Research54, 5579-5583, Nov. 1, 1994.
Emmert-Buck et al, “Allelic Loss on Chromosome 8p12-21 in Microdissected Prostatic Intraepithelial Neoplasia”,Cancer Research55, 2959-2962, Jul. 15, 1995.
Bright et al, “Generation and Characterization of Long-Term Human Prostate Epithelial Cell Lines From Primary Cancer Specimens”, Abstract Keystone Symposia Presentation, Feb. 2, 1996.
Bright et al, “Generation and genetic characterization of immortal human prostate epithelial cell lines derived from primary cancer specimens”,Cancer Research57(5):995-1002, Mar. 1, 1997.
Bright Robert K.
Linehan W. Marston
Topalian Suzanne L.
Vocke Cathy D.
Davis Minh-Tam
Leydig , Voit & Mayer, Ltd.
The United States of America as represented by the Department of
Ungar Susan
LandOfFree
Immortal human prostate epithelial cell lines and clones and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immortal human prostate epithelial cell lines and clones and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immortal human prostate epithelial cell lines and clones and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3596074