Immortal human mammary epithelial cell sublines

Details Immortal human mammary epithelial cell sublines Immortal human mammary epithelial cell sublines

1991-07-09

1993-08-24

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352401, C12N 500, C12N 508

Patent

active

052388409

ABSTRACT:
Two immortalized human mammary epithelial cell sublines are provided. The sublines do not undergo terminal differentiation and senescence upon exposure to high calcium concentrations. The sublines exhibit positive reactivity with milk-fat globule membrane and cytokeratin anti-sera and are non-tumorigenic in athymic mice. The sublines are useful in evaluating the capacity of preselected agents to bring about a change in epithelial cell growth and in the production of proteins.

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In Vitro Cellular and Developmental Biology, vol. 22, No. 1 (Jan. 1986).
Abstract 1780, Proc. AACR, vol. 29, 448 (Mar. 1988).

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