Immobilized polyethylene oxide star molecules for bioapplication

Details Immobilized polyethylene oxide star molecules for bioapplication Immobilized polyethylene oxide star molecules for bioapplication

1992-06-12

1994-01-04

Beck, Shrive

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

525937, 523106, G02C 704

Patent

active

052758389

ABSTRACT:
A method for immobilizing polyethylene oxide (PEO) star molecules in the form of hydrogel layers and a product thereof are disclosed. The PEO star molecules are biocompatible and demonstrate non-thrombogenic properties. As such, the PEO star molecule layers have numerous biomedical applications, such as on contact lenses. The hydrogel layers contain a high percentage of terminal hydroxyl groups for attachment of affinity ligands and can be used for separating and purifying therapeutic proteins.

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