Immobilized metal colloids on dispersed polymer microspheres

Details Immobilized metal colloids on dispersed polymer microspheres Immobilized metal colloids on dispersed polymer microspheres

1993-09-09

1996-09-03

Lovering, Richard D.

Compositions

Nonreactive analytical, testing, or indicating compositions

2523152, 42721331, 427214, 42840224, 428403, 428407, B01J 1322, B32B 1508, B32B 1516, G01N 3352

Patent

active

055520863

ABSTRACT:
The invention describes stable colloidal polymeric particles of 0.2-5.0 microns size which are coated with a first aminodextran layer and a second metallic solid layer, The metal is coated by reduction of a metallic salt or complex by the aminodextran. The metal coated particles, which preferably are gold- or silver-coated polymeric microspheres, produce side scatter and forward shifts in flow cytometry applications that are in agreement with the theoretical shifts predicted for solid gold or silver spheres of similar size in flow cytometry applications,

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patent: 5240640 (1993-08-01), Siiman et al.
patent: 5248772 (1993-09-01), Siiman et al.

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