Immobilized labeling compounds and methods

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing

Reexamination Certificate

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Details

C424S001110, C424S001370, C424S001650, C424S009300, C424S009400, C424S009500, C534S014000

Reexamination Certificate

active

07320784

ABSTRACT:
The invention includes methods and compounds for labelling conjugates with metals which comprise the steps of coupling the conjugate to a support surface; introducing a complex-forming metal to the support; and collecting the metal-conjugate complex released from the support. The metal catalyzes cleavage of the conjugate from the support upon complex formation resulting in a solutions substantially free of unlabeled conjugate.

REFERENCES:
patent: 5659041 (1997-08-01), Dunn-Dufault et al.
patent: 5789555 (1998-08-01), Pollak
patent: 6027711 (2000-02-01), Sharma
patent: 6406297 (2002-06-01), Raymond et al.
patent: 6921526 (2005-07-01), Hoffman et al.
patent: WO 93 17719 (1993-09-01), None
patent: WO 96 037427 (1996-02-01), None
patent: WO 99 40947 (1999-08-01), None
Golub et al., Science, Oct. 15, 1999, pp. 531-537.
Smith, C.J. et al. “Evaluation of a Novel N3S Chelation System for the Preparation of Tc-99m and Re-188 Labeled Biomolecules,”J. Nuclear Med. (May 1998)) vol. 39, No. 5 Suppl.:215 : 45th Annual Meeting of the Society of Nuclear Medicine, Toronto, Ontario, Canada Jun. 7-11, 1998 Society of Nuclear Medicine.
Wong, Ernest et al. “Synthesis and Structural Characterization of Tc-99m and Re oxo Complexes with N1-N′2S1Peptidic Ligands.”J. Nuclear Med., (1997) vol. 38, No. 5 Supp.:148: 44th Annual Meeting of the Society of Nuclear Medicine, San Antonio, Texas, USA, Jun. 1-5, 1997.
Pollak, A., et al., “Inflammation with Novel Peptidic Technetium-99m Chelators Linked to a Chemotactic Peptide”, J. Nuclear Med., vol. 35 (5) Suppl. Jun. 1994, 44P-45P, Proceedings of the 41st Annual Meeting, New York City, NY.
Knight, L.C., :Thrombus Imaging with Technetium-99m Synthetic Peptides Based upon the Binding of a Monoclonal Antibody to Activated Platelets, J. Nuclear Med. vol. 95 (2) Feb. 1994, 282-288.

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