Immobilized fluorogenic substrates for enzymes; and processes fo

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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435 23, 435 24, 530330, 530331, 530300, C08L 8900

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active

048974447

ABSTRACT:
An immobilized fluorogenic substrate useful in processes for identifying and quantifying, intra- and extra-cellularly, and mammalian body fluids, as well as animal cell abstracts is disclosed. The immobilized fluorogenic substrate has the structure

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Paul J. Brynes et al., "6-Aminoquinoline as a Fluorogenic Leaving Group in Peptide Cleavage Reactions: A New Fluorogenic Substrate for Chymotrypsin.sup.1 ", Analytical Biochemistry 116, 408-413 (1981).
Paul J. Brynes et al., "Sensitive Fluorogenic Substrates for the Detection of Trypsinlike Proteases and Pancreatic Elastase", Analytical Biochemistry 126, 447-455 (1982).
Patricia Andrade-Gordon et al., "Synthesis and Kinetic Studies of Protease Substrates Containing the 1-Methyl-6-Aminoquinolinium Ion as A Fluorogenic Leaving Group", Journal of Medical Chemistry 27, 1166 (1984).

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