Immobilized cofactor-dependent enzymes

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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435189, 435190, 435193, 435195, 435233, C12N 904, C12N 1100, C12N 1102, C12N 1118

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058079262

ABSTRACT:
An oxido-reducto synthesis is carried out in a liquid medium with enzymatic transformation of a substrate with an oxido-reducto cofactor dependent enzyme in the presence of a cofactor for the transformation; the enzyme is immobilized by a support which is stationarily disposed in a flow path along which a liquid medium containing the substrate flows in contact with the support.

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Bradshaw, C.W. et al, "Enzymatic Synthesis of (R) and (S) 1-deuterohexanol" Applied Biochemistry and Biotechnology, vol. 33, No. 1, Apr. 1992, pp. 15-24, XP002053169.
Miyawaki, O., et al, "Experimental Investigation of Continuous NAD recycling by Conjugated Enzymes . . ." Journal of Chemical Engineering of Japan, vol. 15, No. 3, Jun. 1982, pp. 224-228.
Campbell, J. et al. "The Recycling of NAD+ (free and immobilized) with Semipermeable . . . Biochemical and Biophysical Research Communications, vol. 69, No. 2, 1976, pp. 562-569.
Haslegrave, J.A. et al, "Enzymes in Organic Synthesis. 25. Heterocyclic Ketones as . . . Journal of the American Chemical Society, vol. 104, 1982, pp. 4666-4671.

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