Immobilized cell reactor-separator with simultaneous product sep

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435288, 435813, 435819, C12P 714, C12M 140

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046650270

ABSTRACT:
A novel immobilized cell reactor design is described capable of separating an inhibitory metabolite from a fermentation broth as it is formed. This reactor has the dual advantages of (1) speeding product inhibited reactions and (2) giving a concentrated product free of substrate and cells. The immobilized cell reactor separator (ICRS) can consist of two columns; in the first or `enriching` column stripping gas and broth move co-currently after which the liquid phase moves to the top of the second `stripping` column and moves counter currently to the stripping gas while the remaining substrate is converted to product. The use of this reactor in an ethanol from whey lactose fermentation system is also described.

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