Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...
Patent
1988-02-25
1990-06-05
Kight, III, John
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Mixing of two or more solid polymers; mixing of solid...
530345, 530811, 530812, 530813, 530814, 530815, 210656, 210927, 428402, 428403, 428406, 428407, A61K 3702, C08G28300, C08L 8900
Patent
active
049314980
ABSTRACT:
Methods and materials are described for the preparation of novel immobilized membrane compositions. The described compositions are useful for evaluating membrane association charcteristics of chemical compounds, and as a chromatographic support material for separation/purification of biomolecules and particularly those expressed by genetically transformed cells as novel hybrid proteins having covalently bound membrane-binding peptides. Novel phospholipid carboxylates are useful intermediates for the preparation of chromatography supports having surfaces formed as covalently bound artificial membranes which simulate natural cellular membranes. The immobilized membrane compositions are adapted for use in chromatographic systems to study interactions of biologically active substances with membranes in vitro. The immobilized membranes are expected to find use for vaccine production, protein purification, chiral separations/synthesis, as a combination reverse phase
ormal phase HPLC support material, and for drug screening.
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Kight III John
Nutter Nathan M.
Purdue Research Foundation
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