Immobilized aminoacylase

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an...

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435106, 435108, 435113, 435180, 435181, C12N 1108, C12N 1106, C12N 1114, C12P 1304

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active

043906265

ABSTRACT:
An immobilized aminoacylase is prepared by bonding aminoacylase to a water-insoluble porous anion exchanger such as a porous phenolic resin, porous styrene resin, porous silica or porous glass having anion exchange groups and treating the bonded amino-acylase with a crosslinking agent such as an aliphatic dialdehyde. The porous anion exchanger preferably has a pore size of about 150.degree. to 3,000 A.degree., pore volume of about 0.3 to 1.0 m.sup.1 /g, specific surface area of about 10 to 150 m.sup.2 /g and particle size of above 0.1 to 1.2 mm. Preferred anion exchangers are trimethylammonium-introduced styrene resin and trimethylammonium-introduced silica.

REFERENCES:
patent: 3767531 (1973-10-01), Olson et al.
patent: 3915797 (1975-10-01), Ishimatsu et al.
patent: 4170696 (1979-10-01), Hirohara et al.
patent: 4239854 (1980-12-01), Hirohara et al.

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