Immobilized aminoacylase

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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435106, 435178, C12N 1102, C12N 1110, C12P 1304

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active

042244110

ABSTRACT:
An immobilized aminoacylase preparation is obtained by adsorbing tannin on a water-insoluble, hydrophilic carrier to give a water-insoluble tannin preparation, adsorbing aminoacylase on the tannin preparation to give a water-insoluble tannin-aminoacylase preparation, and then binding ferric or ferrous ion thereto. The immobilized preparation obtained above sustains a high rate of enzymatic activity for a long period of time when used in an enzymatic reaction thereof with N-acyl-DL-amino acids.

REFERENCES:
patent: 3386888 (1968-06-01), Chibata et al.
patent: 4008124 (1977-02-01), Fujita et al.
patent: 4090919 (1978-05-01), Chibeta et al.
Birnbaum, S. M., Aminoacylase, Methods In Enzymology, vol. II, Academic Press, Inc., New York, 1955, (pp. 115-119).

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