Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-06-05
1997-10-14
Russel, Jeffrey E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 13, 514 14, 514 15, 514 16, 514 17, 530322, 530326, 530327, 530328, 530329, 530330, 530345, 530411, A61K 3808, A61K 3810, A61K 3814, C07K 1113
Patent
active
056772769
ABSTRACT:
The present invention provides novel conjugates of a synthetic polypeptide containing RGD or (dR)GD and a biodegradable polymer, hyaluronate. The conjugates are prepared by any one of three different methods provided by the present invention: (1) an epoxide method (2) a sodium periodate method, and (3) a tresyl chloride method. The conjugates prepared by these methods are useful to aid in wound healing and tissue regeneration by providing a temporary matrix for tissue repair. The invention also provides novel RGD-peptides.
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Cheng Soan
Craig William S.
Dickerson Kenneth T.
Glass James R.
Liu Lin-Shu
La Jolla Cancer Research Foundation
Russel Jeffrey E.
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