Immobilization of oligonucleotides onto solid supports

Details Immobilization of oligonucleotides onto solid supports Immobilization of oligonucleotides onto solid supports

2007-06-12

2007-06-12

Riley, Jezia (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S006120, C536S025330

Reexamination Certificate

active

10475298

ABSTRACT:
A solid support bound polynucleotide, preferably a 3′-O- or 5′-O-substituted polynucleotide, is disclosed. The polynucleotides are of formula:wherein Q is a substantially pure polynucleotide, each X is O or S; Y is an inert spacer group; R represents the solid support. Also disclosed is a method of isolating a target biomolecule, preferably a protein or a polynucleotide, from a mixture.

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