Immobilization of nucleic acids

Details Immobilization of nucleic acids Immobilization of nucleic acids

2006-02-07

2006-02-07

Naff, David M. (Department: 1651)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S180000, C530S402000, C530S815000, C536S124000

Reexamination Certificate

active

06995248

ABSTRACT:
This invention relates to a biomolecule-bound substrate made of polymeric molecules, each of which contains a reacting group; and a plurality of biomolecules, each of which contains another reacting group. One of the two reacting groups is a substitute group and the other is a leaving group; and the biomolecules are covalently bonded to the solid support via a chemical ligation reaction between the two reacting groups.

REFERENCES:
patent: 3849253 (1974-11-01), Harrey et al.
patent: 4614714 (1986-09-01), Kusakabe et al.
patent: 4764466 (1988-08-01), Suyama et al.
patent: 5789219 (1998-08-01), Bieniarz et al.
patent: 5981734 (1999-11-01), Mirzabekov et al.
patent: 6171797 (2001-01-01), Perbost
patent: 6498245 (2002-12-01), Kimura et al.
patent: 0 390 500 (1990-10-01), None
patent: 0 403 700 (1990-12-01), None
patent: 0 390 500 (1992-07-01), None
patent: 1 035 218 (2000-09-01), None
patent: WO 96/35699 (1996-11-01), None
patent: WO 01/16372 (2001-03-01), None
patent: WO 01/40310 (2001-06-01), None
Zaborsky, O., Immobilized Enzymes, CRC Press, Cleveland, Ohio, 1973, pp. 14, 15, 20, 25 & 27.
Lemieux, et al., TIBTECH, vol. 16, Dec. 1998, pp. 506-513.
Basu et al., “Solid Phase Synthesis of a D-Peptide-Phosphorothioate Oligodeoxynucleotide Conjugate from Two Arms of a Polyethylene Glycol-Polystyrene Support”, Tetrahedron Letters 36:4943-4946, 1995.
Database WPI Section Ch. Week 199149 Derwent Publications Ltd., London, GB; AN 1991-356630, XP002195605 & JP 03 237147 A (Mitsubishi Kasei Vinyl KK), Oct. 23, 1991 abstract.
Yanzheng Xu and Eric T. Kool.High sequence fidelity in a non-enzymatic DNA autoligation reaction. Nucleic Acids Research, 1999, vol. 27, No. 3. pp. 875-881.

Affiliated with

Also associated with

Rating

Immobilization of nucleic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immobilization of nucleic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immobilization of nucleic acids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3641008