Immobilization of cells with a polyazetidine prepolymer

Details Immobilization of cells with a polyazetidine prepolymer Immobilization of cells with a polyazetidine prepolymer

1983-02-10

1988-03-22

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound having a 1-thia-4-aza-bicyclo

435 41, 435 52, 435 94, 435108, 435109, 435116, 435180, 435182, C12P 3700, C12P 100, C12N 1108, C12N 1104

Patent

active

047328517

ABSTRACT:
A composition comprising immobilized cells obtained by applying a dispersion of cells and curable prepolymer material selected from the group consisting of polyazetidine prepolymers, carboxymethyl cellulose, polyurethane hydrogel prepolymers and polymethylene isocyanates. as a coating to a solid inert carrier and curing the prepolymer on the carrier at a temperature below the temperature at which enzyme activity of the cells is significantly reduced. The composition may be used to produce various materials such as L-aspartic acid, L-alanine, 6-Aminopenicillanic acid, high fructose corn syrup, prednisolone or phenylalanine.

REFERENCES:
patent: 3791926 (1974-02-01), Chibata et al.
patent: 3860490 (1975-01-01), Guttag
patent: 4138292 (1979-02-01), Chibata et al.
patent: 4237229 (1980-12-01), Hartdegen
patent: 4436813 (1984-03-01), Wood et al.
Fusee, et al., Applied and Environmental Microbiology, vol. 42, No. 4, 1981 (pp. 672-676).
Hustad, et al., J. Dz. Sci., vol. 56, No. 9, 1973 (pp. 1111-1117).

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